N-[(2,5-dimethoxyphenyl)methyl]-4-phenoxy-1H-indazol-3-amine

Base Information

Chemical Name:N-[(2,5-dimethoxyphenyl)methyl]-4-phenoxy-1H-indazol-3-amine
CAS No.:816454-27-0
Molecular Formula:C₂₂H₂₁N₃O₃
Molecular Weight:375.427
Hs Code.:
ChEMBL ID:CHEMBL359806
DSSTox Substance ID:DTXSID201186996

Synonyms:CHEMBL359806;N-[(2,5-dimethoxyphenyl)methyl]-4-phenoxy-1H-indazol-3-amine;816454-27-0;DTXSID201186996;BDBM50422608

Suppliers and Price of N-[(2,5-dimethoxyphenyl)methyl]-4-phenoxy-1H-indazol-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[(2,5-dimethoxyphenyl)methyl]-4-phenoxy-1H-indazol-3-amine

Chemical Property:

Boiling Point:591.2±45.0 °C(Predicted)
Density:1.277±0.06 g/cm3(Predicted)
XLogP3:4.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:375.15829154
Heavy Atom Count:28
Complexity:474

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)OC)CNC2=NNC3=C2C(=CC=C3)OC4=CC=CC=C4

Technology Process of N-[(2,5-dimethoxyphenyl)methyl]-4-phenoxy-1H-indazol-3-amine

There total 3 articles about N-[(2,5-dimethoxyphenyl)methyl]-4-phenoxy-1H-indazol-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₁₉N₃O₃

: 816454-27-0
N-(2,5-dimethoxybenzyl)-4-phenoxy-1H-indazol-3-amine

Guidance literature:: With (polystyrylmethyl)trimethylammonium cyanoborohydride; acetic acid; In acetonitrile; at 20 ℃; for 2h;

Reference yield:

: 175204-06-5
2-phenoxy-6-fluorobenzonitrile

: 816454-27-0
N-(2,5-dimethoxybenzyl)-4-phenoxy-1H-indazol-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol

2: sodium triacetoxyborohydride; AcOH / methanol

With sodium tris(acetoxy)borohydride; hydrazine hydrate; acetic acid; In methanol; ethanol;
DOI:10.1016/j.bmcl.2005.05.008