4-{2-[(1R,2R)-1-amino-2-hydroxypropyl]imidazo[1,2-a]pyridin-6-yl}benzonitrile formate

Base Information

Chemical Name:4-{2-[(1R,2R)-1-amino-2-hydroxypropyl]imidazo[1,2-a]pyridin-6-yl}benzonitrile formate
CAS No.:1449474-50-3
Molecular Formula:CH₂O₂*C₁₇H₁₆N₄O
Molecular Weight:338.366
Hs Code.:

Synonyms:4-{2-[(1R,2R)-1-amino-2-hydroxypropyl]imidazo[1,2-a]pyridin-6-yl}benzonitrile formate

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Chemical Property of 4-{2-[(1R,2R)-1-amino-2-hydroxypropyl]imidazo[1,2-a]pyridin-6-yl}benzonitrile formate

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Technology Process of 4-{2-[(1R,2R)-1-amino-2-hydroxypropyl]imidazo[1,2-a]pyridin-6-yl}benzonitrile formate

There total 1 articles about 4-{2-[(1R,2R)-1-amino-2-hydroxypropyl]imidazo[1,2-a]pyridin-6-yl}benzonitrile formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1449475-83-5
tert-butyl (4S,5R)-4-(bromoacetyl)-2,2,5-trimethyl-1,3-oxazolidine-3-carboxylate

: 503536-78-5
4-(6-aminopyridin-3-yl)benzonitrile

: 1449474-50-3
4-{2-[(1R,2R)-1-amino-2-hydroxypropyl]imidazo[1,2-a]pyridin-6-yl}benzonitrile formate

Guidance literature:: tert-butyl (4S,5R)-4-(bromoacetyl)-2,2,5-trimethyl-1,3-oxazolidine-3-carboxylate; 4-(6-aminopyridin-3-yl)benzonitrile; In tetrahydrofuran; for 18h; Reflux;

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 5h;