(2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran

Base Information

Chemical Name:(2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran
CAS No.:1426683-84-2
Molecular Formula:C₄₁H₆₄ClNO₁₁
Molecular Weight:782.412
Hs Code.:

Synonyms:(2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran

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Technology Process of (2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran

There total 1 articles about (2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 120255-31-4
C₃₃H₄₈ClNO₉

: 67-63-0,8013-70-5
isopropyl alcohol

: 1426683-84-2
(2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran

Guidance literature:: With scandium tris(trifluoromethanesulfonate); In chloroform; at -40 ℃; for 24h; diastereoselective reaction; Inert atmosphere;
DOI:10.1002/adsc.201200761

Reference yield:

: 1426683-84-2
(2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran

: 1426683-93-3
(2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(amino)methyl]tetrahydro-2H-pyran

: (2S,3S)-2-isopropoxy-3-[(R)-4-chlorophenyl(amino)methyl]tetrahydro-2H-pyran

Guidance literature:: (2R,3R)-2-isopropoxy-3-[(S)-4-chlorophenyl(2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamino)methyl]tetrahydro-2H-pyran; With sodium methylate; In methanol;

With water; acetic acid; In methanol; for 4h;
DOI:10.1002/adsc.201200761