5-Methyl-3-(trifluoromethyl)isoxazole

Base Information

Chemical Name:5-Methyl-3-(trifluoromethyl)isoxazole
CAS No.:111079-03-9
Molecular Formula:C₅H₄F₃NO
Molecular Weight:151.088
Hs Code.:
DSSTox Substance ID:DTXSID30406117
Wikidata:Q82211008
Mol file:111079-03-9.mol

Synonyms:5-methyl-3-(trifluoromethyl)isoxazole;111079-03-9;5-methyl-3-(trifluoromethyl)-1,2-oxazole;Isoxazole, 5-methyl-3-(trifluoromethyl)- (9CI);SBB039333;Isoxazole, 5-methyl-3-(trifluoromethyl)-;SCHEMBL8130541;DTXSID30406117;PQKSCGVOQVRTEH-UHFFFAOYSA-N;AKOS000267811;FS-6296;CS-0335373;5-Methyl-3-(trifluoromethyl)-1,2-oxazole (stabilized over potassium carbonate)

Suppliers and Price of 5-Methyl-3-(trifluoromethyl)isoxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
5-Methyl-3-(trifluoromethyl)-1,2-oxazole(stabilizedoverpotassiumcarbonate) 96%
1g
$ 273.00

Crysdot
5-Methyl-3-(trifluoromethyl)isoxazole 95+%
5g
$ 769.00

American Custom Chemicals Corporation
5-METHYL-3-(TRIFLUOROMETHYL)ISOXAZOLE 95.00%
5MG
$ 504.94

Total 3 raw suppliers

Chemical Property of 5-Methyl-3-(trifluoromethyl)isoxazole

Chemical Property:

PSA：26.03000
LogP:2.00180
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:151.02449824
Heavy Atom Count:10
Complexity:125

Purity/Quality:

99%+ ^*data from raw suppliers

5-Methyl-3-(trifluoromethyl)-1,2-oxazole(stabilizedoverpotassiumcarbonate) 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NO1)C(F)(F)F

Technology Process of 5-Methyl-3-(trifluoromethyl)isoxazole

There total 2 articles about 5-Methyl-3-(trifluoromethyl)isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 367-57-7
1,1,1-Trifluoro-2,4-pentanedione

: 111079-03-9
5-methyl-3-(trifluoromethyl)isoxazole

: 161144-75-8
5-methyl-3-trifluoromethylisoxazole

Guidance literature:: With sulfuric acid; hydroxylamine; In ethanol; Title compound not separated from byproducts;
DOI:10.1016/S0022-1139(02)00221-X

Reference yield:

: 5-Methyl-3-trifluoromethyl-isoxazole-4-carboxylic acid methyl ester

: 111079-03-9
5-methyl-3-(trifluoromethyl)isoxazole

Guidance literature:: With copper; sodium carbonate; Yield given. Multistep reaction; 1.) ethanol, water, reflux, 12 h, 2.) quinoline, 190 deg C, 3 h;
DOI:10.1246/bcsj.59.2631