5-oxo-N-phenylpyrrolidine-2-carboxamide

Base Information

Chemical Name:5-oxo-N-phenylpyrrolidine-2-carboxamide
CAS No.:5626-54-0
Molecular Formula:C11H12 N2 O2
Molecular Weight:204.23
Hs Code.:
NSC Number:42356
DSSTox Substance ID:DTXSID701031778
ChEMBL ID:CHEMBL1726841

Synonyms:5-oxo-N-phenylpyrrolidine-2-carboxamide;5626-54-0;5-oxo-N-phenylprolinamide;5-Oxo-pyrrolidine-2-carboxylic acid phenylamide;NSC42356;CBMicro_000424;5-OXO-N-PHENYL-2-PYRROLIDINECARBOXAMIDE;Cambridge id 5878458;Oprea1_280279;MLS000529074;SCHEMBL2222173;CHEMBL1726841;DTXSID701031778;HMS1693K04;HMS2327N12;SMSF0009050;BBL020237;MFCD01897586;NSC-42356;STK889360;AKOS001632547;CB01978;CCG-108298;SMR000121549;2-pyrrolidinecarboxamide, 5-oxo-N-phenyl-;BIM-0000619.P001;CS-0322915;SR-01000455051;SR-01000455051-1

Suppliers and Price of 5-oxo-N-phenylpyrrolidine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Oxo-N-phenyl-2-pyrrolidinecarboxamide
10mg
$ 60.00

Crysdot
5-Oxo-N-phenylpyrrolidine-2-carboxamide 97%
250mg
$ 452.00

Total 4 raw suppliers

Chemical Property of 5-oxo-N-phenylpyrrolidine-2-carboxamide

Chemical Property:

Melting Point:204 °C
Boiling Point:535.1±43.0 °C(Predicted)
PSA：58.20000
Density:1.277±0.06 g/cm3(Predicted)
LogP:1.30550
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:204.089877630
Heavy Atom Count:15
Complexity:259

Purity/Quality:

99% ^*data from raw suppliers

5-Oxo-N-phenyl-2-pyrrolidinecarboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC1C(=O)NC2=CC=CC=C2

Technology Process of 5-oxo-N-phenylpyrrolidine-2-carboxamide

There total 7 articles about 5-oxo-N-phenylpyrrolidine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30274-77-2
oxoproline TMS

: 5626-54-0
5-oxopyrrolidine-2-carboxanilide

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent Spectr_. / CH₂Cl₂ / 0.08 h / 0 °C

2: SOCl₂ / CH₂Cl₂ / 2 h / Heating

3: CH₂Cl₂

With thionyl chloride; In dichloromethane;
DOI:10.1002/jhet.5570320532

Reference yield:

: trimethylsilyl N-trifluoroacetylpyroglutamate

: 5626-54-0
5-oxopyrrolidine-2-carboxanilide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / CH₂Cl₂ / 2 h / Heating

2: CH₂Cl₂

With thionyl chloride; In dichloromethane;
DOI:10.1002/jhet.5570320532

Reference yield:

: 1676-73-9,25014-27-1
L-glutamic acid γ-benzyl ester

: 5626-54-0
5-oxopyrrolidine-2-carboxanilide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / Inert atmosphere

2.1: dicyclohexyl-carbodiimide / Inert atmosphere

3.1: trifluoroacetic acid / dichloromethane / Inert atmosphere

3.2: Inert atmosphere

With triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane;
DOI:10.1039/c7cc01440f