2-[4-((R)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]-2,3-dihydro-1H-isoindole

Base Information

Chemical Name:2-[4-((R)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]-2,3-dihydro-1H-isoindole
CAS No.:942427-20-5
Molecular Formula:C₂₀H₂₄N₂O
Molecular Weight:308.423
Hs Code.:

Synonyms:2-[4-((R)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]-2,3-dihydro-1H-isoindole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[4-((R)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]-2,3-dihydro-1H-isoindole

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Technology Process of 2-[4-((R)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]-2,3-dihydro-1H-isoindole

There total 1 articles about 2-[4-((R)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]-2,3-dihydro-1H-isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 942427-42-1
(R)-2-[4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-phenoxymethyl]-pyrrolidine-1-carboxylic acid tert-butyl ester

: 942427-20-5
2-[4-((R)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]-2,3-dihydro-1H-isoindole

Guidance literature:: (R)-2-[4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-phenoxymethyl]-pyrrolidine-1-carboxylic acid tert-butyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 - 78 ℃; for 26h;

With sodium hydroxide; water; In tetrahydrofuran; at 5 ℃;