7-Chloro-5-phenyl-3-piperidin-1-yl-3H-benzo[e][1,4]diazepine

Base Information

• Chemical Name: 7-Chloro-5-phenyl-3-piperidin-1-yl-3H-benzo[e][1,4]diazepine
• CAS No.: 84505-15-7
• Molecular Formula: C₂₀H₂₀ClN₃
• Molecular Weight: 337.852
• Mol file: 84505-15-7.mol

Synonyms:7-Chloro-5-phenyl-3-piperidin-1-yl-3H-benzo[e][1,4]diazepine

Chemical Property of 7-Chloro-5-phenyl-3-piperidin-1-yl-3H-benzo[e][1,4]diazepine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-Chloro-5-phenyl-3-piperidin-1-yl-3H-benzo[e][1,4]diazepine

There total 1 articles about 7-Chloro-5-phenyl-3-piperidin-1-yl-3H-benzo[e][1,4]diazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(2-amino-5-chlorophenyl)-phenyl-methane-imine (5606-39-3) + N,N'-ethanediylidenedipiperidinium dibromide (30098-99-8) → 7-Chloro-5-phenyl-3-piperidin-1-yl-3H-benzo[e][1,4]diazepine (84505-15-7)

Guidance literature:

With triethylamine; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1055/s-1982-29948

Reference yield:

7-Chloro-5-phenyl-3-piperidin-1-yl-3H-benzo[e][1,4]diazepine (84505-15-7) → 7-Chloro-5-phenyl-3-piperidin-1-yl-2,3-dihydro-1H-benzo[e][1,4]diazepine (84505-19-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 0.25h; Yield given;

DOI:10.1055/s-1982-29948

upstream raw materials:

(2-amino-5-chlorophenyl)-phenyl-methane-imine

N,N'-ethanediylidenedipiperidinium dibromide

Downstream raw materials:

7-Chloro-5-phenyl-3-piperidin-1-yl-2,3-dihydro-1H-benzo[e][1,4]diazepine