methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate

Base Information

Chemical Name:methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate
CAS No.:1430086-23-9
Molecular Formula:C₂₀H₂₁N₃O₅
Molecular Weight:383.404
Hs Code.:

Synonyms:methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate

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Chemical Property of methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate

Chemical Property:

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Technology Process of methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate

There total 5 articles about methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₁₉N₃O₅

: 18107-18-1
diazomethyl-trimethyl-silane

: 1430086-23-9
methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate

Guidance literature:: In methanol; diethyl ether; at 20 ℃; for 0.5h; Inert atmosphere;

Reference yield:

: 1430086-22-8
ethyl 2-benzyl-3-hydrazinyl-2-hydroxy-3-oxopropanoate

: 1430086-23-9
methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / butan-1-ol / 1.5 h / 160 °C / Inert atmosphere

1.2: pH 1 / Acidic conditions

2.1: methanol; diethyl ether / 0.5 h / 20 °C / Inert atmosphere

With potassium carbonate; In methanol; diethyl ether; butan-1-ol;

Reference yield:

: 19179-31-8
3,5-dimethoxy-benzonitrile

: 1430086-23-9
methyl 2-[5-(3,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]-2-hydroxy-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / butan-1-ol / 1.5 h / 160 °C / Inert atmosphere

1.2: pH 1 / Acidic conditions

2.1: methanol; diethyl ether / 0.5 h / 20 °C / Inert atmosphere

With potassium carbonate; In methanol; diethyl ether; butan-1-ol;