2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)-, (1R)- (9CI)

Base Information

Chemical Name:2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)-, (1R)- (9CI)
CAS No.:110568-59-7
Molecular Formula:C₈H₈F₃NO₂
Molecular Weight:207.152
Hs Code.:
Mol file:110568-59-7.mol

Synonyms:2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)-, (1R)- (9CI)

Suppliers and Price of 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)-, (1R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)-, (1R)- (9CI)

Chemical Property:

PSA：29.54000
LogP:1.34760

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)-, (1R)- (9CI)

There total 1 articles about 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)-, (1R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121156-84-1
(1R,4S)-(+)-2-Oxa-3-azabicyclo<2.2.2>oct-5-en

: 407-25-0
trifluoroacetic anhydride

: 110568-59-7,110658-87-2
(1R,4S)-(-)-3-(Trifluoracetyl)-2-oxa-3-azabicyclo<2.2.2>oct-5-en

Guidance literature:: With dmap; In pyridine; dichloromethane; for 20h; Yield given; Ambient temperature;

Reference yield: 71.0%

: 110568-59-7,110658-87-2
(1R,4S)-(-)-3-(Trifluoracetyl)-2-oxa-3-azabicyclo<2.2.2>oct-5-en

: 110568-60-0
(1R,4S)-(-)-4-(Trifluoracetamido)-2-cyclohexen-1-ol

Guidance literature:: With aluminum amalgam; In tetrahydrofuran; water; for 26h; Ambient temperature;

Reference yield:

: 110568-59-7,110658-87-2
(1R,4S)-(-)-3-(Trifluoracetyl)-2-oxa-3-azabicyclo<2.2.2>oct-5-en

: 110568-61-1
(4S)-(-)-4-(Trifluoracetamido)-2-cyclohexen-1-on

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / Al/Hg / tetrahydrofuran; H₂O / 26 h / Ambient temperature

2: 77 percent / MnO₂ / CH₂Cl₂ / 12 h / Ambient temperature

With manganese(IV) oxide; aluminum amalgam; In tetrahydrofuran; dichloromethane; water;