6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride

Base Information

Chemical Name:6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride
CAS No.:1198109-62-4
Molecular Formula:C₁₁H₉BrCl₂N₄*ClH
Molecular Weight:384.49
Hs Code.:

Synonyms:6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride

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Technology Process of 6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride

There total 1 articles about 6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 39906-04-2
5-amino-4,6-dichloro-2-methylpyrimidine

: 873-38-1
4-chloro-2-bromoaniline

: 1198109-62-4
6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; at 85 ℃;

Reference yield:

: 1445-45-0
Trimethyl orthoacetate

: 1198109-62-4
6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride

: 1198109-63-5
6-chloro-9-(2-bromo-4-chlorophenyl)-2,8-dimethyl-9H-purine

Guidance literature:: With triethylamine; In acetonitrile; at 74 ℃; Inert atmosphere;

Reference yield:

: 1198109-62-4
6-chloro-4-N-(2-bromo-4-chlorophenyl)-2-methylpyrimidine-4,5-diamine hydrochloride

: 1198109-28-2
dicyclopropylmethyl-[9-(4-chloro-2-methoxyphenyl)-2,8-dimethyl-9H-purin-6-yl]-amine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / acetonitrile / 74 °C / Inert atmosphere

2: triethylamine / butan-1-ol / 16 h / Reflux; Inert atmosphere

3: copper(l) iodide / 0.5 h / 120 °C / Microwave irradiation

With copper(l) iodide; triethylamine; In acetonitrile; butan-1-ol;