(-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester

Base Information

• Chemical Name: (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester
• CAS No.: 949890-73-7
• Molecular Formula: C₂₅H₃₁NO₄
• Molecular Weight: 409.525
• Mol file: 949890-73-7.mol

Synonyms:(-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester

Chemical Property of (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester

There total 3 articles about (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2E)-3-phenyl-2-propen-1-ol (4407-36-7) → (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester (949890-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 72 percent / quinine / toluene / 24 h / -30 °C

2.1: triethylamine; diphenylphosphoryl azide / toluene / 20 - 90 °C

2.2: toluene / Heating

With diphenylphosphoranyl azide; triethylamine; Quinine; In toluene;

DOI:10.1016/j.tetasy.2007.06.014

Reference yield:

(-)-(R)-3-isobutyl-pentanedioic acid mono-(3-phenyl-allyl) ester (949890-69-1) + benzyl alcohol (100-51-6,185532-71-2) → (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester (949890-73-7)

Guidance literature:

(-)-(R)-3-isobutyl-pentanedioic acid mono-(3-phenyl-allyl) ester; With diphenylphosphoranyl azide; triethylamine; In toluene; at 20 - 90 ℃;

benzyl alcohol; In toluene; Further stages.; Heating;

DOI:10.1016/j.tetasy.2007.06.014

Reference yield:

3-isobutylglutaric anhydride (185815-59-2) → (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester (949890-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 72 percent / quinine / toluene / 24 h / -30 °C

2.1: triethylamine; diphenylphosphoryl azide / toluene / 20 - 90 °C

2.2: toluene / Heating

With diphenylphosphoranyl azide; triethylamine; Quinine; In toluene;

DOI:10.1016/j.tetasy.2007.06.014

upstream raw materials:

(-)-(R)-3-isobutyl-pentanedioic acid mono-(3-phenyl-allyl) ester

benzyl alcohol

3-isobutylglutaric anhydride

(2E)-3-phenyl-2-propen-1-ol

Downstream raw materials:

(-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid

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