(-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide

Base Information

• Chemical Name: (-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide
• CAS No.: 73377-81-8
• Molecular Formula: C₂₃H₁₆O₃
• Molecular Weight: 340.378
• Mol file: 73377-81-8.mol

Synonyms:(-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide

Chemical Property of (-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide

There total 4 articles about (-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(Diphenylmethyl)-1,4-naphthoquinone (14039-65-7) → (-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide (73377-81-8)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; N-benzylcinchonidinum chloride; In water; toluene; at 35 - 40 ℃;

DOI:10.1021/jo01300a047

Reference yield:

2,2-diphenylacetic acid (117-34-0) → (-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide (73377-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 40 percent / AgNO₃, ammonium persulfate / acetonitrile; tetrahydrothiophene 1,1-dioxide; H₂O / 60 - 65 °C

2: 100 percent / 30percent H₂O₂, NaOH / (-)-Benzylquininium chloride / toluene; H₂O / 35 - 40 °C

With sodium hydroxide; ammonium persulfate; dihydrogen peroxide; silver nitrate; N-benzylcinchonidinum chloride; In sulfolane; water; toluene; acetonitrile;

DOI:10.1021/jo01300a047

Reference yield:

[1,4]naphthoquinone (130-15-4) → (-)-2-(Diphenylmethyl)-1,4-naphthoquinone 2,3-epoxide (73377-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 40 percent / AgNO₃, ammonium persulfate / acetonitrile; tetrahydrothiophene 1,1-dioxide; H₂O / 60 - 65 °C

2: 100 percent / 30percent H₂O₂, NaOH / (-)-Benzylquininium chloride / toluene; H₂O / 35 - 40 °C

With sodium hydroxide; ammonium persulfate; dihydrogen peroxide; silver nitrate; N-benzylcinchonidinum chloride; In sulfolane; water; toluene; acetonitrile;

DOI:10.1021/jo01300a047

upstream raw materials:

2-(Diphenylmethyl)-1,4-naphthoquinone

2,2-diphenylacetic acid

[1,4]naphthoquinone