N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine

Base Information

• Chemical Name: N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine
• CAS No.: 195305-15-8
• Molecular Formula: C₂₀H₂₀N₂O₆
• Molecular Weight: 384.389
• Mol file: 195305-15-8.mol

Synonyms:N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine

Chemical Property of N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine

There total 4 articles about N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N,N'-bis-(4-methoxycarbonylbenzoyl)-1,4-butanediamine (102810-33-3) → N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine (195305-15-8)

Guidance literature:

With potassium hydroxide; In methanol; water; for 3h; Reflux;

DOI:10.4067/S0717-97072012000300023

Reference yield:

Monomethyl terephthalate (1679-64-7) → N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine (195305-15-8)

Guidance literature:

Multi-step reaction with 3 steps

1: dicyclohexyl-carbodiimide / 1,4-dioxane / 10 - 20 °C

2: triethylamine; dmap / N,N-dimethyl-formamide / 12 h / 20 °C

3: potassium hydroxide / water; methanol / 3 h / Reflux

With dmap; triethylamine; dicyclohexyl-carbodiimide; potassium hydroxide; In 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;

DOI:10.4067/S0717-97072012000300023

Reference yield:

N-(4-methoxycarbonylbenzoyloxy)succinimide (264270-90-8) → N,N'-bis-(4-carboxybenzoyl)-1,4-butanediamine (195305-15-8)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine; dmap / N,N-dimethyl-formamide / 12 h / 20 °C

2: potassium hydroxide / water; methanol / 3 h / Reflux

With dmap; triethylamine; potassium hydroxide; In methanol; water; N,N-dimethyl-formamide;

DOI:10.4067/S0717-97072012000300023

upstream raw materials:

methyl 4-formylbenzoate

Monomethyl terephthalate

N-(4-methoxycarbonylbenzoyloxy)succinimide

N,N'-bis-(4-methoxycarbonylbenzoyl)-1,4-butanediamine