4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester

Base Information

Chemical Name:4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester
CAS No.:197144-65-3
Molecular Formula:C₂₈H₂₇NO₄
Molecular Weight:441.527
Hs Code.:

Synonyms:4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester

Suppliers and Price of 4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester

There total 5 articles about 4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 7297-85-0
4-hydroxy-γ-(4-hydroxyphenyl)-γ-methyl-benzenebutanoic acid methyl ester

: 3747-74-8
2-(chloromethyl)quinoline monohydrochloride

: 197144-65-3
4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 48h;
DOI:10.1021/jm000180n

Reference yield:

: 126-00-1
4,4-bis(4-hydroxyphenyl)valeric acid

: 197144-65-3
4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / conc. H₂SO₄ / 3 h / Heating

2: 36 percent / K₂CO₃ / dimethylformamide / 48 h / 20 °C

With sulfuric acid; potassium carbonate; In N,N-dimethyl-formamide; 1: Esterification / 2: Alkylation;
DOI:10.1021/jm000180n

Reference yield:

: 539-88-8
4-oxopentanoic acid ethyl ester

: 197144-65-3
4-(4-hydroxyphenyl)-4-(4'-(2-quinolylmethoxy)phenyl)pentanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄ / H₂O / 18 h / 0 - 20 °C

2: 97 percent / conc. H₂SO₄ / 3 h / Heating

3: 36 percent / K₂CO₃ / dimethylformamide / 48 h / 20 °C

With sulfuric acid; potassium carbonate; In water; N,N-dimethyl-formamide; 1: Condensation / 2: Esterification / 3: Alkylation;
DOI:10.1021/jm000180n