N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide

Base Information

Chemical Name:N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide
CAS No.:1428451-03-9
Molecular Formula:C₁₇H₂₀N₂O₄S
Molecular Weight:348.423
Hs Code.:

Synonyms:N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide

Chemical Property:

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Technology Process of N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide

There total 7 articles about N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1428451-07-3
2-bromo-2',4'-bismethoxycarbonyloxyacetophenone

: 1428451-08-4
N-(4-acetoxymethylcyclohexylcarbonyl)thiourea

: 1428451-03-9
N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / ethanol / 0.5 h / Reflux

2: sodium hydroxide; water / ethanol / 0.5 h / 20 °C

With water; sodium hydrogencarbonate; sodium hydroxide; In ethanol;

Reference yield:

: C₂₃H₂₆N₂O₉S

: 1428451-03-9
N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide

Guidance literature:: With water; sodium hydroxide; In ethanol; at 20 ℃; for 0.5h;

Reference yield:

: 301237-91-2
4-acetoxymethylcyclohexanecarboxylic acid

: 1428451-03-9
N-(4-(2,4-dihydroxyphenyl)thiazol-2-yl)-4-(hydroxymethyl)cyclohexanecarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / 2 h / Reflux

2: toluene / 3 h / Reflux

3: sodium hydrogencarbonate / ethanol / 0.5 h / Reflux

4: sodium hydroxide; water / ethanol / 0.5 h / 20 °C

With thionyl chloride; water; sodium hydrogencarbonate; sodium hydroxide; In ethanol; toluene;