4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Base Information

Chemical Name:4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline
CAS No.:946504-69-4
Molecular Formula:C₂₀H₂₀FN₃OS
Molecular Weight:369.463
Hs Code.:

Synonyms:4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

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Technology Process of 4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

There total 1 articles about 4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 4079-68-9,125678-52-6
N,N-diethyl-2-propynylamine

: 918643-41-1
3-Fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)aniline

: 946504-69-4
4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Guidance literature:: With triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 40 ℃; for 18h;

Reference yield: 31.0%

: 946504-69-4
4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

: 29313-32-4
2-phenylacetyl isothiocyanate

: N-(4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-2-phenylacetamide

: N-(4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenylcarbamothioyl)-2-phenylacetamide

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; ethanol; toluene; at 20 ℃; for 0.5h;

Reference yield: 8.0%

: 946504-69-4
4-(2-(3-(diethylamino)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

: 3-fluoro-4-(2-propylthieno[3,2-b]pyridin-7-yloxy)benzenamine

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated carbon; In 1,4-dioxane; ethanol; dichloromethane; at 20 ℃; for 18h; under 2585.81 Torr;