Methyl 2-(2-oxoindolin-5-YL)acetate

Base Information

Chemical Name:Methyl 2-(2-oxoindolin-5-YL)acetate
CAS No.:109737-05-5
Molecular Formula:C₁₁H₁₁NO₃
Molecular Weight:205.213
Hs Code.:
DSSTox Substance ID:DTXSID30697381
Wikidata:Q82627266
Mol file:109737-05-5.mol

Synonyms:109737-05-5;METHYL 2-(2-OXOINDOLIN-5-YL)ACETATE;METHYL 2-(2-OXO-1,3-DIHYDROINDOL-5-YL)ACETATE;SCHEMBL10722015;DTXSID30697381;KTOPVPVMLRSPHW-UHFFFAOYSA-N;AKOS015909456;2-(2-Oxoindolin-5-yl)acetic acid methyl ester;A802079;Methyl (2-oxo-2,3-dihydro-1H-indol-5-yl)acetate;1H-Indole-5-aceticacid,2,3-dihydro-2-oxo-,methyl ester;2-(2-oxo-1,3-dihydroindol-5-yl)acetic acid methyl ester

Suppliers and Price of Methyl 2-(2-oxoindolin-5-YL)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Methyl 2-(2-oxoindolin-5-YL)acetate

Chemical Property:

PSA：58.89000
LogP:0.98180
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:205.07389321
Heavy Atom Count:15
Complexity:277

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1=CC2=C(C=C1)NC(=O)C2

Technology Process of Methyl 2-(2-oxoindolin-5-YL)acetate

There total 2 articles about Methyl 2-(2-oxoindolin-5-YL)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 2-oxo-2-(2-oxoindolin-5-yl)acetic acid methyl ester

: 109737-05-5
2-(2-oxoindolin-5-yl)acetic acid methyl ester

Guidance literature:: With palladium 10% on activated carbon; hydrogen; trifluoroacetic acid; at 50 ℃; for 4h; under 4500.45 Torr;

Reference yield:

: 59-48-3
2-oxoindole

: 109737-05-5
2-(2-oxoindolin-5-yl)acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / 1,2-dichloro-ethane / 0.5 h / 20 °C / Inert atmosphere; Cooling

2: trifluoroacetic acid; palladium 10% on activated carbon; hydrogen / 4 h / 50 °C / 4500.45 Torr

With aluminum (III) chloride; palladium 10% on activated carbon; hydrogen; trifluoroacetic acid; In 1,2-dichloro-ethane;