Zolpidem Carboxylic Acid

Base Information

• Chemical Name: Zolpidem Carboxylic Acid
• CAS No.: 109461-65-6
• Molecular Formula: C19H19 N3 O3
• Molecular Weight: 337.37
• UNII: OGV9R9660K
• DSSTox Substance ID: DTXSID50148941
• Nikkaji Number: J373.198G
• Wikidata: Q27285649
• Mol file: 109461-65-6.mol

Synonyms:ZCA cpd;zolpidem carboxylic acid

Chemical Property of Zolpidem Carboxylic Acid

Chemical Property:

• Melting Point: >200?C (dec.)
• Flash Point: 13℃
• PSA: 74.91000
• LogP: 4.63360
• Storage Temp.: Controlled Substance, -20°C Freezer
• Solubility.: Methanol (Slightly, Heated)
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 337.14264148
• Heavy Atom Count: 25
• Complexity: 502

Purity/Quality:

99%+, ^*data from raw suppliers

Zolpidem phenyl-4-carboxylic acid solution 500?μg/mL in acetonitrile: water (1:1), ampule of 1?mL, certified reference material, Cerilliant? ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xn
• Hazard Codes: F,Xn
• Statements: 11-20/21/22-36
• Safety Statements: 16-26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CN2C(=NC(=C2CC(=O)N(C)C)C3=CC=C(C=C3)C(=O)O)C=C1

Technology Process of Zolpidem Carboxylic Acid

There total 1 articles about Zolpidem Carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

ethyl 4-[(3-dimethylcarbamoylmethyl-6-methyl)imidazo[1,2-a]pyridin-2-yl]benzoate (1026465-13-3) → SL 84.0589 (109461-65-6)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1248/cpb.54.1318

upstream raw materials:

ethyl 4-[(3-dimethylcarbamoylmethyl-6-methyl)imidazo[1,2-a]pyridin-2-yl]benzoate

Refernces