2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine

Base Information

• Chemical Name: 2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine
• CAS No.: 153390-74-0
• Molecular Formula: C₂₃H₃₆N₂O₂Si₂
• Molecular Weight: 428.722
• Mol file: 153390-74-0.mol

Synonyms:2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine

Chemical Property of 2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine

There total 2 articles about 2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

2,3-bis(hydroxyamino)-2,3-dimethylbutane monosulfate (14538-51-3,78375-92-5) + 3,5‐bis((trimethylsilyl)ethynyl)benzaldehyde (153390-73-9) → 2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine (153390-74-0)

Guidance literature:

In benzene; at 25 ℃; for 36h;

Reference yield:

3,5-dibromobenzaldehyde (56990-02-4) → 2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine (153390-74-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / Ph₃P, Et₃N, Pd(II) acetate / 3 h / Heating

2: 43 percent / benzene / 36 h / 25 °C

With palladium diacetate; triethylamine; triphenylphosphine; In benzene;

Reference yield: 87.0%

2-(3,5-bis(trimethylsilylethynyl)phenyl)-1,3-dihydroxy-4,4,5,5-tetramethylimidazolidine (153390-74-0) → 2-(3,5-bis(trimethylsilylethynyl)phenyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-oxide (153390-75-1)

Guidance literature:

With lead dioxide; In chloroform; at 25 ℃; for 0.0833333h;

upstream raw materials:

2,3-bis(hydroxyamino)-2,3-dimethylbutane monosulfate

3,5‐bis((trimethylsilyl)ethynyl)benzaldehyde

3,5-dibromobenzaldehyde

Downstream raw materials:

2-(3,5-bis(trimethylsilylethynyl)phenyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-oxide