Technology Process of 2-acetylamino-3,3-diphenylacrylic acid methyl ester
There total 4 articles about 2-acetylamino-3,3-diphenylacrylic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutylammomium bromide; potassium carbonate;
palladium diacetate;
In
ethanol;
at 20 ℃;
for 8h;
DOI:10.1055/s-2003-37338
- Guidance literature:
-
With
potassium phosphate monohydrate; palladium diacetate; DavePhos;
In
tetrahydrofuran; water;
at 70 ℃;
for 2h;
Sealed tube;
Inert atmosphere;
DOI:10.1021/ja511872a
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triethylamine; N-Bromosuccinimide / dichloromethane / Inert atmosphere
2: DavePhos; potassium phosphate monohydrate; palladium diacetate / water; tetrahydrofuran / 2 h / 70 °C / Sealed tube; Inert atmosphere
With
N-Bromosuccinimide; potassium phosphate monohydrate; palladium diacetate; triethylamine; DavePhos;
In
tetrahydrofuran; dichloromethane; water;
2: |Suzuki-Miyaura Coupling;
DOI:10.1021/ja511872a
