N-(2,6-DIMETHYLPHENYL)MALEAMIC ACID

Base Information

• Chemical Name: N-(2,6-DIMETHYLPHENYL)MALEAMIC ACID
• CAS No.: 109017-95-0
• Molecular Formula: C12H13 N O3
• Molecular Weight: 219.24
• Mol file: 109017-95-0.mol

Synonyms:Fumaranilicacid, 2',6'-dimethyl- (6CI)

Chemical Property of N-(2,6-DIMETHYLPHENYL)MALEAMIC ACID

Chemical Property:

• PSA: 66.40000
• LogP: 1.95570

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2,6-DIMETHYLPHENYL)MALEAMIC ACID

There total 2 articles about N-(2,6-DIMETHYLPHENYL)MALEAMIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fumaryl dichloride (627-63-4) + 2,6-dimethylaniline (87-62-7) → Fumarsaeure-mono-2,6-dimethyl-anilid (109017-95-0)

Guidance literature:

fumaryl dichloride; 2,6-dimethylaniline; With sodium hydroxide;

With hydrogenchloride;

DOI:10.1016/j.bmcl.2010.01.098

Reference yield:

→ Fumarsaeure-mono-2,6-dimethyl-anilid (109017-95-0)

Guidance literature:

Maleinsaeure-mono-2,6-dimethyl-anilid, Bzl. (od. Xylol), Δ;

Reference yield: 81.0%

Fumarsaeure-mono-2,6-dimethyl-anilid (109017-95-0) + (3E,5E)-3,5-bis[(4-nitrophenyl)methylidene]piperidin-4-one (919091-63-7) → C31H26N4O7

Guidance literature:

Fumarsaeure-mono-2,6-dimethyl-anilid; With triethylamine; In tetrahydrofuran; at 20 ℃; for 0.5h;

(3E,5E)-3,5-bis[(4-nitrophenyl)methylidene]piperidin-4-one; In tetrahydrofuran; at 20 ℃; for 17h; Further stages.;

DOI:10.1016/j.bmc.2007.05.065

upstream raw materials:

fumaryl dichloride

2,6-dimethylaniline

Downstream raw materials:

Methyl N-(2,6-dimethylphenyl)fumaramate

Refernces