(1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile

Base Information

Chemical Name:(1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile
CAS No.:142923-90-8
Molecular Formula:C₂₀H₂₇NO₂S
Molecular Weight:345.506
Hs Code.:

Synonyms:(1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile

Suppliers and Price of (1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile

There total 5 articles about (1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 142835-85-6
(1R,2R,αR,Rs)-(+)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfinylcyclohexaneacetonitrile

: 142923-90-8
(1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1016/S0040-4020(01)80539-1

Reference yield:

: 63923-58-0
(R)-(+)-cyanomethyl p-tolyl sulfoxide

: 142923-90-8
(1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / piperidinium acetate, molecular sieves 4A / benzene / 24 h / Ambient temperature

2: CH₂Cl₂ / 2 h / -20 °C / diastereoselectivity, Et₂AlCl catalyzed intramolecular ene reaction, other Lewis acids, solvents, temperatures

3: 98 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 1 h / 0 °C

With 4 A molecular sieve; piperdinium acetate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; benzene;
DOI:10.1016/S0040-4020(01)80539-1

Reference yield:

: 17920-90-0
3,3,7-trimethyl-oct-6-enal

: 142923-90-8
(1R,2R,αR)-(-)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfonylcyclohexaneacetonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / piperidinium acetate, molecular sieves 4A / benzene / 24 h / Ambient temperature

2: CH₂Cl₂ / 2 h / -20 °C / diastereoselectivity, Et₂AlCl catalyzed intramolecular ene reaction, other Lewis acids, solvents, temperatures

3: 98 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 1 h / 0 °C

With 4 A molecular sieve; piperdinium acetate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; benzene;
DOI:10.1016/S0040-4020(01)80539-1