2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Base Information

Chemical Name:2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one
CAS No.:83800-92-4
Molecular Formula:C₁₄H₁₁ClN₂O
Molecular Weight:258.707
Hs Code.:
European Community (EC) Number:653-910-0
Nikkaji Number:J3.042.781E
ChEMBL ID:CHEMBL1527371

Synonyms:2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one;83800-92-4;BAS 00739634;Oprea1_147679;Oprea1_724992;MLS000693162;2-(3-chlorophenyl)-1,2,3,4-tetrahydroquinazolin-4-one;CHEMBL1527371;2-(3-CHLOROPHENYL)-1,2-DIHYDRO-4(3H)-QUINAZOLINONE;HMS2609C16;STK826066;AKOS000544476;SMR000284801;Z48978376;2-(3-Chlorophenyl)-1,2-dihydroquinazoline-4(3H)-one

Suppliers and Price of 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:258.0559907
Heavy Atom Count:18
Complexity:323

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)NC(N2)C3=CC(=CC=C3)Cl

Technology Process of 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

There total 6 articles about 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 587-04-2
m-Chlorobenzaldehyde

: 28144-70-9,88-68-6
anthranilic acid amide

: 83800-92-4
2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With Amberlyst-15; In acetonitrile; at 20 ℃; for 0.166667h;
DOI:10.1016/j.tetlet.2011.12.023

Reference yield: 94.0%

: 118-48-9
isatoic anhydride

: 587-04-2
m-Chlorobenzaldehyde

: 83800-92-4
2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With ammonium acetate; L-proline; In water; at 100 ℃; for 0.116667h; Microwave irradiation;

Reference yield: 90.0%

: 70288-97-0
1-chloro-3-(dibromomethyl)benzene

: 28144-70-9,88-68-6
anthranilic acid amide

: 83800-92-4
2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With pyridine; potassium tert-butylate; In N,N-dimethyl-formamide; at 80 ℃; for 4h; Reagent/catalyst; Temperature;
DOI:10.1039/c4ra02312a