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Technology Process of Ramipril Diketopiperazine

Ramipril Diketopiperazine

Base Information
  • Chemical Name:Ramipril Diketopiperazine
  • CAS No.:108731-95-9
  • Molecular Formula:C23H30 N2 O4
  • Molecular Weight:398.5
  • Hs Code.:
  • European Community (EC) Number:642-122-2
  • UNII:U3O93H26WI
  • DSSTox Substance ID:DTXSID001312563
  • Nikkaji Number:J1.380.340D
  • Wikidata:Q27290645
  • Mol file:108731-95-9.mol
Ramipril Diketopiperazine

Synonyms:Ramipril Diketopiperazine;108731-95-9;Ramipril-diketopiperazine;U3O93H26WI;Ethyl (2S)-2-((3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta(4,5)pyrrolo(1,2-a)pyrazin-2-yl)-4-phenylbutanoate;ethyl (2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoate;Ramipril impurity;Ethyl (2S)-2-[(3S,5aS,8aS,9aS)-3-Methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoate (Ramipril Diketopiperazine);UNII-U3O93H26WI;Ramipril specified impurity D [EP];Ramipril impurity D;SCHEMBL13484396;KOVMAAYRBJCASY-JBDAPHQKSA-N;DTXSID001312563;2H-Cyclopenta(4,5)pyrrolo(1,2-a)pyrazine-2-acetic acid, decahydro-3-methyl-1,4-dioxo-alpha-(2-phenylethyl)-, ethyl ester, (alphaS,3S,5aS,8aS,9aS)-;RAMIPRIL IMPURITY D [EP IMPURITY];Q27290645;(S)-Ethyl 2-((3S,5aS,8aS,9aS)-3-methyl-1,4-dioxooctahydro-1H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2(5aH)-yl)-4-phenylbutanoate;[3S-[2(R*),3A,5Ab,8Ab,9Ab]]-Decahydro-3-methyl-1,4-Dioxo-A-(2-Phenylethyl)-2H-Cyclopenta[4,5]Pyrrolo[1,2-A]Pyrazine-2-Acetic Acid Ethyl Ester;2H-CYCLOPENTA(4,5)PYRROLO(1,2-A)PYRAZINE-2-ACETIC ACID, DECAHYDRO-3-METHYL-1,4-DIOXO-.ALPHA.-(2-PHENYLETHYL)-, ETHYL ESTER, (.ALPHA.S,3S,5AS,8AS,9AS)-

Suppliers and Price of Ramipril Diketopiperazine
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • RamiprilDiketopiperazine
  • 1mg
  • $ 110.00
  • Sigma-Aldrich
  • Ramipril Related Compound D
  • 20mg
  • $ 1160.00
  • Sigma-Aldrich
  • Ramipril impurity D European Pharmacopoeia (EP) Reference Standard
  • r0145020
  • $ 190.00
  • AvaChem
  • Ramipril Diketopiperazine
  • 25mg
  • $ 575.00
  • AvaChem
  • Ramipril Diketopiperazine
  • 10mg
  • $ 275.00
  • AvaChem
  • Ramipril Diketopiperazine
  • 5mg
  • $ 175.00
  • American Custom Chemicals Corporation
  • RAMIPRIL DIKETOPIPERAZINE 95.00%
  • 10MG
  • $ 2887.50
  • American Custom Chemicals Corporation
  • RAMIPRIL DIKETOPIPERAZINE 95.00%
  • 1MG
  • $ 899.85
Total 13 raw suppliers
Chemical Property of Ramipril Diketopiperazine
Chemical Property:
  • Refractive Index:1.588 
  • PSA：66.92000 
  • LogP:2.42700 
  • Storage Temp.:2-8°C 
  • XLogP3:3.4
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:7
  • Exact Mass:398.22055744
  • Heavy Atom Count:29
  • Complexity:645
Purity/Quality:

99%, *data from raw suppliers

RamiprilDiketopiperazine *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CCOC(=O)C(CCC1=CC=CC=C1)N2C(C(=O)N3C4CCCC4CC3C2=O)C
  • Isomeric SMILES:CCOC(=O)[C@H](CCC1=CC=CC=C1)N2[C@H](C(=O)N3[C@H]4CCC[C@H]4C[C@H]3C2=O)C
  • Uses A metabolite of Ramipril (R111000). Ramipril Diketopiperazine (Ramipril EP Impurity D) is a metabolite of Ramipril (R111000).
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