(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

Base Information

Chemical Name:(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester
CAS No.:261963-24-0
Molecular Formula:C₂₁H₂₃NO₅
Molecular Weight:369.417
Hs Code.:

Synonyms:(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

Suppliers and Price of (-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

There total 1 articles about (-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: (R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid potassium salt

: 19967-55-6
1-bromo-3-methyl-2-butanone

: 261963-24-0
(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 15h;
DOI:10.1016/S0040-4020(99)00935-7

Reference yield:

: 261963-24-0
(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

: 2026-48-4,473-75-6
(S)-valinol

Guidance literature:: Multi-step reaction with 4 steps

1: hydrobromic acid; acetic acid

2: potassium carbonate

3: sodium triacetoxyborohydride; chlorotrimethylsilane / acetonitrile / 4 h / 20 °C

4: 88 percent / hydrogen / Pd/C / methanol / 72 h / 114000 Torr

With chloro-trimethyl-silane; hydrogen bromide; hydrogen; sodium tris(acetoxy)borohydride; potassium carbonate; acetic acid; palladium on activated charcoal; In methanol; acetonitrile; 1: Hydrolysis / 2: Cyclization / 3: Reduction / 4: Hydrogenolysis;
DOI:10.1016/S0040-4020(99)00935-7

Reference yield:

: 261963-24-0
(-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 3-methyl-2-oxo-butyl ester

: 157985-11-0
(5S)-5-isopropyl-3-phenyl-5,6-dihydro-2H-1,4-oxazine-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: hydrobromic acid; acetic acid

2: potassium carbonate

3: sodium triacetoxyborohydride; chlorotrimethylsilane / acetonitrile / 4 h / 20 °C

With chloro-trimethyl-silane; hydrogen bromide; sodium tris(acetoxy)borohydride; potassium carbonate; acetic acid; In acetonitrile; 1: Hydrolysis / 2: Cyclization / 3: Reduction;
DOI:10.1016/S0040-4020(99)00935-7