2,4-Dichlorophenethyl bromide

Base Information

• Chemical Name: 2,4-Dichlorophenethyl bromide
• CAS No.: 108649-59-8
• Molecular Formula: C8H7 Br Cl2
• Molecular Weight: 253.954
• Hs Code.: 2903999090
• European Community (EC) Number: 626-131-9
• DSSTox Substance ID: DTXSID40445794
• Wikidata: Q82264323
• Mol file: 108649-59-8.mol

Synonyms:108649-59-8;1-(2-Bromoethyl)-2,4-dichlorobenzene;2,4-Dichlorophenethyl bromide;2 4-dichlorophenethyl bromide;Benzene, 1-(2-bromoethyl)-2,4-dichloro-;MFCD07369774;SCHEMBL1779915;DTXSID40445794;BJTSTVKJPXWNIY-UHFFFAOYSA-N;2,4-Dichlorophenethyl bromide, 96%;AKOS014197344;AB92909;BS-22806;SY272654;CS-0156858;FT-0707039;C77752;EN300-696356;A895208

Chemical Property of 2,4-Dichlorophenethyl bromide

Chemical Property:

• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: n20/D 1.584(lit.)
• Boiling Point: 271.622°C at 760 mmHg
• Flash Point: >230 °F
• PSA: 0.00000
• Density: 1.5721 g/mL at 25 °C(lit.)
• LogP: 3.93080
• Storage Temp.: 2-8°C
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 251.91082
• Heavy Atom Count: 11
• Complexity: 119

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4-Dichlorophenethyl bromide 96% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-41
• Safety Statements: 26-39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)Cl)CCBr

Technology Process of 2,4-Dichlorophenethyl bromide

There total 2 articles about 2,4-Dichlorophenethyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-dichlorophenylethyl alcohol (81156-68-5) → 1-(2-bromoethyl)-2,4-dichlorobenzene (108649-59-8)

Guidance literature:

With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 0.416667h;

DOI:10.1021/jm960167w

Reference yield:

→ 1-(2-bromoethyl)-2,4-dichlorobenzene (108649-59-8)

Guidance literature:

Reference yield: 93.0%

1-(2-bromoethyl)-2,4-dichlorobenzene (108649-59-8) → 2,4-dichlorophenylethyl azide (1443040-00-3)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 60 ℃; for 10h;

DOI:10.1016/j.ejmech.2013.03.004

upstream raw materials:

2,4-dichlorophenylethyl alcohol

Downstream raw materials:

Thioacetic acid S-[2-(2,4-dichloro-phenyl)-ethyl] ester

4-[2-(2,4-Dichloro-phenyl)-ethylsulfanyl]-3-oxo-butyric acid methyl ester

3-Cyano-4-[2-(2,4-dichloro-phenyl)-ethylsulfanyl]-3-hydroxy-butyric acid methyl ester

sodium 2-(2,4-dichlorophenyl)ethanesulphonate

Refernces

• 1、 -. "PYRROLOPYRIMIDINE DERIVATIVES USEFUL AS MODULATORS OF MULTIDRUG RESISTANCE". Page 49. . Retrieved 2010/02/07.