(5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

Base Information

Chemical Name:(5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline
CAS No.:934240-42-3
Molecular Formula:C₂₃H₂₇NO₅
Molecular Weight:397.471
Hs Code.:

Synonyms:(5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

Suppliers and Price of (5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

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Chemical Property of (5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

Chemical Property:

Boiling Point:563.4±50.0 °C(Predicted)
Density:1.211±0.06 g/cm3(Predicted)

Purity/Quality:

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Technology Process of (5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

There total 1 articles about (5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 934240-41-2
(5R)-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

: 24424-99-5
di-tert-butyl dicarbonate

: 934240-42-3
(5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

Guidance literature:: (5R)-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline; di-tert-butyl dicarbonate; In tetrahydrofuran; at 20 ℃; for 3.5h;

With hydrogenchloride; In tetrahydrofuran; water; pH=3;

Reference yield: 87.0%

: 934240-42-3
(5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

: 934240-43-4
1,1-dimethylethyl (2S,5R)-2-(aminocarbonyl)-5-{4-[(phenylmethyl)oxy]phenyl}-1-pyrrolidinecarboxylate

Guidance literature:: (5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 0.333333h;

With 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; at 20 ℃; for 2h;

With sodium hydrogencarbonate; In tetrahydrofuran; water; for 0.5h;

Reference yield: 87.0%

: 934240-42-3
(5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline

: 934240-56-9
1,1-dimethylethyl (2R,5S)-2-(aminocarbonyl)-5-{4-[(phenylmethyl)oxy]phenyl}-1-pyrrolidinecarboxylate

Guidance literature:: (5R)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-5-{4-[(phenylmethyl)oxy]phenyl}-L-proline; With 1-[bis(dimethylamino)methylen]-1-H-benzotriazolim-tetrafluoroborate-3-oxide; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 0.333333h;

With 1,1,1,3,3,3-hexamethyl-disilazane; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

With sodium hydrogencarbonate; In water; N,N-dimethyl-formamide; for 0.5h;