2-oxo-N,3-diphenylpropanamide

Base Information

• Chemical Name: 2-oxo-N,3-diphenylpropanamide
• CAS No.: 6362-61-4
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.274
• Mol file: 6362-61-4.mol

Synonyms:2-oxo-N,3-diphenylpropanamide

Chemical Property of 2-oxo-N,3-diphenylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-oxo-N,3-diphenylpropanamide

There total 12 articles about 2-oxo-N,3-diphenylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-oxo-3-(phenyl)propionic acid (156-06-9) + phenyl isocyanate (103-71-9) → 2-oxo-N,3-diphenylpropanamide (6362-61-4)

Guidance literature:

In neat (no solvent); at 25 ℃; Sealed tube;

DOI:10.1039/d1ob00562f

Reference yield: 85.0%

2-oxo-3-(phenyl)propionic acid (156-06-9) + benzoyl azide (582-61-6) → 2-oxo-N,3-diphenylpropanamide (6362-61-4)

Guidance literature:

at 60 ℃; for 8h;

Reference yield: 62.0%

2-Benzotriazol-1-yl-2-carbazol-9-yl-3,N-diphenyl-propionamide (136617-26-0) → 2-oxo-N,3-diphenylpropanamide (6362-61-4)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; for 24h; Ambient temperature;

DOI:10.1021/jo00024a039

upstream raw materials:

phenyl-oxalacetic acid-anhydride

aniline

2-Benzotriazol-1-yl-2-carbazol-9-yl-3,N-diphenyl-propionamide

1-(1-Methylsulfanyl-2-phenyl-ethyl)-1H-benzotriazole

Downstream raw materials:

N,2,3-triphenylacrylamide

(3S,4R)-5-nitro-2-oxo-N,3,4-triphenylpentanamide

(3S,4R)-4-(4-fluorophenyl)-5-nitro-2-oxo-N,3-diphenylpentanamide

(3S,4R)-4-(4-methoxyphenyl)-5-nitro-2-oxo-N,3-diphenylpentanamide