(R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane

Base Information

• Chemical Name: (R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane
• CAS No.: 1567768-26-6
• Molecular Formula: C₃₂H₅₂O₂
• Molecular Weight: 468.764
• Mol file: 1567768-26-6.mol

Synonyms:(R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane

Chemical Property of (R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane

There total 1 articles about (R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

propargyl bromide (106-96-7) + Tocopherol (59-02-9,18920-62-2) → (R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane (1567768-26-6)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;

DOI:10.1021/acscombsci.0c00060

Reference yield: 85.0%

(R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane (1567768-26-6) + benzyl azide (622-79-7) → 1-benzyl-4-((((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl)oxy)methyl)-1H-1,2,3-triazole

Guidance literature:

With copper(I) iodide; In water; acetonitrile; at 70 ℃; for 5h; regioselective reaction; Green chemistry;

DOI:10.1021/acscombsci.0c00060

Reference yield: 83.0%

(R)-2,5,7,8-tetramethyl-6-(prop-2-yn-1-yloxy)-2-((4R,8R)-4,8,12-trimethyltridecyl)chromane (1567768-26-6) + SS-tert-butyl p-toluenesulfono(dithioperoxoate) + benzyl azide (622-79-7) → C43H67N3O2S2

Guidance literature:

With copper(l) iodide; lithium tert-butoxide; In tetrahydrofuran; at 40 ℃; for 12h; regioselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1021/acs.orglett.8b01002

upstream raw materials:

propargyl bromide

Tocopherol