Technology Process of (4S,6S)-4-benzyloxy-6-benzyloxymethyltetrahydropyran-2-one
There total 6 articles about (4S,6S)-4-benzyloxy-6-benzyloxymethyltetrahydropyran-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Celite;
In
toluene;
Heating;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 80 percent / tetrahydrofuran / Ambient temperature; overnight
2: 95 percent / Amberlite IR 118 (H(1+)) / methanol / Ambient temperature
3: 1.) sodium hydride / 1.) THF, 0 deg C, room temp., 2 h; 2.) THF, room temp, overnight
4: 62 percent / 1M hydrochloric acid / tetrahydrofuran / 7 h / Heating
5: 93 percent / Ag2CO, Celite (Fetizons reagent) / toluene / Heating
With
hydrogenchloride; Amberlite IR 118 (H(1+)); Celite; sodium hydride;
In
tetrahydrofuran; methanol; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) lithium triethylborohydride; 2.) sodium hydroxide, 30percent aq. hydrogen peroxide / 1.) THF, 20 deg C, 4 days; 2.) room temp., 4 h
2: 80 percent / tetrahydrofuran / Ambient temperature; overnight
3: 95 percent / Amberlite IR 118 (H(1+)) / methanol / Ambient temperature
4: 1.) sodium hydride / 1.) THF, 0 deg C, room temp., 2 h; 2.) THF, room temp, overnight
5: 62 percent / 1M hydrochloric acid / tetrahydrofuran / 7 h / Heating
6: 93 percent / Ag2CO, Celite (Fetizons reagent) / toluene / Heating
With
hydrogenchloride; sodium hydroxide; Amberlite IR 118 (H(1+)); Celite; dihydrogen peroxide; sodium hydride; lithium triethylborohydride;
In
tetrahydrofuran; methanol; toluene;
