delapril hydrochloride

Base Information

Chemical Name:delapril hydrochloride
CAS No.:108428-40-6
Molecular Formula:C26H32 N2 O5 . Cl H
Molecular Weight:0
Hs Code.:
Mol file:108428-40-6.mol

Synonyms:Glycine, N-(2,3-dihydro-1H-inden-2-yl)-N-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, monohydrochloride, (R)-

Suppliers and Price of delapril hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of delapril hydrochloride

Chemical Property:

PSA：95.94000
LogP:3.80250

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of delapril hydrochloride

There total 6 articles about delapril hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 83435-63-6
N--L-alanyl>-N-(indan-2-yl)glycine

: 108428-40-6
N--L-alanyl>-N-(indan-2-yl)glycine

Guidance literature:: With hydrogenchloride; sodium hydrogencarbonate; In water; ethyl acetate;
DOI:10.1248/cpb.34.2852

Reference yield:

: 64920-29-2
2-oxo-4-phenylbutanoic acid ethyl ester

: 108428-40-6
N--L-alanyl>-N-(indan-2-yl)glycine

Guidance literature:: Multi-step reaction with 5 steps

1: 29 percent / H₂, AcONa, AcOH, molecular sieves 3A / Raney Ni / ethanol

2: 98 percent / HCl / H₂O / 4 h

3: 73 percent / diethyl phosphorocyanidate, Et₃N / dimethylformamide / 1 h

4: 57 percent / HBr-AcOH / acetic acid / 10 h

5: 76 percent / NaHCO₃, 7N HCl / ethyl acetate; H₂O

With hydrogenchloride; diethyl cyanophosphonate; 3 A molecular sieve; hydrogen bromide; hydrogen; sodium acetate; sodium hydrogencarbonate; acetic acid; triethylamine; nickel; In ethanol; water; acetic acid; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.34.2852

Reference yield:

: 83402-63-5
tert-butyl N-(2,3-dihydro-1H-inden-2-yl)glycinate

: 108428-40-6
N--L-alanyl>-N-(indan-2-yl)glycine

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / diethyl phosphorocyanidate, Et₃N / dimethylformamide / 1 h

2: 57 percent / HBr-AcOH / acetic acid / 10 h

3: 76 percent / NaHCO₃, 7N HCl / ethyl acetate; H₂O

With hydrogenchloride; diethyl cyanophosphonate; hydrogen bromide; sodium hydrogencarbonate; acetic acid; triethylamine; In water; acetic acid; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.34.2852