Chemical Property of SUCCINYL COENZYME A SODIUM SALT
Chemical Property:
- PSA：468.30000
- LogP:-0.67090
- Storage Temp.:−20°C
- Purity/Quality:
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98%,99%, *data from raw suppliers
Succinyl coenzyme A sodium salt ≥85% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
22-26-36
- MSDS Files:
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SDS file from LookChem
Useful:
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Description
Succinyl-coenzyme A (succinyl-CoA) is an intermediate in the citric acid cycle. It is converted to succinate, which is a metabolic intermediate with various biological activities. Succinyl-CoA is required, with glycine, to form δ-aminolevulinic acid in the first step of porphyrin and heme synthesis. Succinyl-CoA deficiency, caused by vitamin B12 deficiency can disrupt heme and energy production, leading to neuromotor dysfunction.
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Uses
Succinyl coenzyme A sodium salt has been used: for the nonenzymatic succinylation of lysine in vitro, as a substrate for adipic acid biosynthesis in recombinant E. coli in isocitrate dehydrogenase (ICDH)?treatment for the succinylation of proteinsas a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)
