N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane

Base Information

• Chemical Name: N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane
• CAS No.: 208718-97-2
• Molecular Formula: C₁₅H₂₅N
• Molecular Weight: 219.37
• Mol file: 208718-97-2.mol

Synonyms:N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane

Chemical Property of N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane

There total 4 articles about N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-tert-butyl-2,6-dimethylphenylacetonitrile (84803-57-6) → N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane (208718-97-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 76 percent / H₂ / 10percentPd/C / methanol / 2068.6 Torr

2: Et₃N / tetrahydrofuran / Ambient temperature

3: LiAlH₄ / tetrahydrofuran / 4 h / Heating

With lithium aluminium tetrahydride; hydrogen; triethylamine; 10% palladium on active carbon; In tetrahydrofuran; methanol;

DOI:10.1021/jm970513p

Reference yield:

Benzyl-[2-(4-tert-butyl-2,6-dimethyl-phenyl)-ethyl]-methyl-amine; hydrochloride → N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane (208718-97-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr; Ambient temperature;

Reference yield:

[2-(4-tert-Butyl-2,6-dimethyl-phenyl)-ethyl]-carbamic acid ethyl ester → N-monomethyl-2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane (208718-97-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Heating;

DOI:10.1021/jm970513p

upstream raw materials:

4-tert-butyl-2,6-dimethylphenylacetonitrile

2-(2,6-dimethyl-4-tert-butylphenyl)-1-aminoethane