methyl 4-((4-cyclohexyl benzyl)amino)benzoate

Base Information

Chemical Name:methyl 4-((4-cyclohexyl benzyl)amino)benzoate
CAS No.:719290-14-9
Molecular Formula:C₂₁H₂₅NO₂
Molecular Weight:323.435
Hs Code.:

Synonyms:methyl 4-((4-cyclohexyl benzyl)amino)benzoate

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Chemical Property of methyl 4-((4-cyclohexyl benzyl)amino)benzoate

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Technology Process of methyl 4-((4-cyclohexyl benzyl)amino)benzoate

There total 5 articles about methyl 4-((4-cyclohexyl benzyl)amino)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₃H₂₄F₃NO₃

: 719290-14-9
methyl 4-((4-cyclohexyl benzyl)amino)benzoate

Guidance literature:: With potassium carbonate; In tetrahydrofuran; methanol;
DOI:10.1021/acs.jmedchem.0c01705

Reference yield:

: 208259-47-6
4-cyclohexylphenylmethyl alcohol

: 719290-14-9
methyl 4-((4-cyclohexyl benzyl)amino)benzoate

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / dichloromethane / 3 h / 20 °C / Inert atmosphere

2: sodium iodide; potassium carbonate / acetonitrile / 60 °C / Inert atmosphere

3: potassium carbonate / methanol; tetrahydrofuran

With thionyl chloride; potassium carbonate; sodium iodide; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1021/acs.jmedchem.0c01705

Reference yield:

: 56345-18-7
1-(p-hydroxymethylphenyl)cyclohexene

: 719290-14-9
methyl 4-((4-cyclohexyl benzyl)amino)benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen; platinum(IV) oxide / ethyl acetate; methanol / 4 h

2: thionyl chloride / dichloromethane / 3 h / 20 °C / Inert atmosphere

3: sodium iodide; potassium carbonate / acetonitrile / 60 °C / Inert atmosphere

4: potassium carbonate / methanol; tetrahydrofuran

With platinum(IV) oxide; thionyl chloride; hydrogen; potassium carbonate; sodium iodide; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate; acetonitrile;
DOI:10.1021/acs.jmedchem.0c01705