(2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

Base Information

Chemical Name:(2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol
CAS No.:741265-59-8
Molecular Formula:C₄₁H₄₂O₉
Molecular Weight:678.779
Hs Code.:

(2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

Synonyms:(2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

Suppliers and Price of (2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

There total 18 articles about (2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1187196-29-7
C₅₆H₅₀O₁₂

: 741265-59-8
(2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

Guidance literature:: With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 - -20 ℃;

Reference yield: 90.0%

: C₅₇H₅₂O₁₂

: 741265-59-8
(2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

Guidance literature:: With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 - -20 ℃; for 0.166667h; Inert atmosphere;
DOI:10.1021/acs.orglett.9b01099

Reference yield:

: (5S,6S)-1,5,8-Tris-benzyloxy-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracene-3,6-diol

: 741265-59-8
(2S,3S,6S)-6-((5S,6S)-1,8-Bis-benzyloxy-5-hydroxy-3-hydroxymethyl-7,12-dimethoxy-5,6-dihydro-benzo[a]anthracen-6-yloxy)-2-methyl-tetrahydro-pyran-3-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: 98 percent / K₂CO₃ / acetone / 3 h / 0 °C

2.1: 91 percent / dppp; Et₃N / Pd(OAc)2 / dimethylformamide / 30 h / 65 °C / 2280 Torr

3.1: BF₃*OEt₂; molecular sieves 4 Angstroem / CH₂Cl₂

3.2: DIBAL / CH₂Cl₂ / 1 h / -78 - -20 °C

With 4 A molecular sieve; boron trifluoride diethyl etherate; 1,3-bis-(diphenylphosphino)propane; potassium carbonate; triethylamine; palladium diacetate; In dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1002/anie.200453801