Technology Process of (E)-3-phenyl-2-propenyl (E)-3-(1-triphenylmethylimidazol-4-yl)-2-propenyl ether
There total 4 articles about (E)-3-phenyl-2-propenyl (E)-3-(1-triphenylmethylimidazol-4-yl)-2-propenyl ether which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-(1-Trityl-1H-imidazol4-yl)propen-3-ol;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
for 1h;
Inert atmosphere;
Cooling with ice;
cinnamyl chloride;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
Inert atmosphere;
Cooling with ice;
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
Inert atmosphere;
DOI:10.1039/c0ob00657b
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: diisobutylaluminium hydride
2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / Inert atmosphere; Cooling with ice
2.2: 20 °C / Inert atmosphere; Cooling with ice
2.3: 20 °C / Inert atmosphere
With
sodium hydride; diisobutylaluminium hydride;
In
tetrahydrofuran; mineral oil;
DOI:10.1039/c0ob00657b
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sulfuric acid; magnesium sulfate / Reflux
2.1: triethylamine / N,N-dimethyl-formamide
3.1: diisobutylaluminium hydride
4.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / Inert atmosphere; Cooling with ice
4.2: 20 °C / Inert atmosphere; Cooling with ice
4.3: 20 °C / Inert atmosphere
With
sulfuric acid; sodium hydride; diisobutylaluminium hydride; magnesium sulfate; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
1.1: Fischer esterification;
DOI:10.1039/c0ob00657b