C₂₁H₃₀O

Base Information

• Chemical Name: C₂₁H₃₀O
• CAS No.: 238072-73-6
• Molecular Formula: C₂₁H₃₀O
• Molecular Weight: 298.469
• Mol file: 238072-73-6.mol

Synonyms:C₂₁H₃₀O

Chemical Property of C₂₁H₃₀O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₃₀O

There total 13 articles about C₂₁H₃₀O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(1R,2S,7S)-6-[(E)-1-Methyl-3-(2,6,6-trimethyl-cyclohex-1-enyl)-prop-2-en-(E)-ylidene]-bicyclo[5.1.0]octan-2-ol (238072-72-5) → C21H30O (238072-73-6)

Guidance literature:

With pyridine-SO₃ complex; triethylamine; In dimethyl sulfoxide; at 20 ℃; for 0.666667h;

DOI:10.1021/ol990048l

Reference yield:

C10H14O3 (238072-67-8) → C21H30O (238072-73-6)

Guidance literature:

Multi-step reaction with 7 steps

1.1: NaH / tetrahydrofuran; various solvent(s) / 0.33 h / 20 °C

1.2: 91 percent / tetrahydrofuran; various solvent(s) / 1 h / 20 °C

2.1: 96 percent / K₂CO₃; MeOH / 2 h / 20 °C

3.1: 96 percent / imidazole; DMAP / CH₂Cl₂ / 2 h / 20 °C

4.1: DIBAL-H / diethyl ether; hexane / 5 h / -78 °C

5.1: BuLi / tetrahydrofuran; hexane / 0.17 h / 20 °C

5.2: 90 percent / tetrahydrofuran; hexane / 20 °C

6.1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 4 h / 70 °C

7.1: 80 percent / SO₃-pyridine; Et₃N / dimethylsulfoxide / 0.67 h / 20 °C

With 1H-imidazole; methanol; dmap; n-butyllithium; pyridine-SO₃ complex; tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; potassium carbonate; triethylamine; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; dimethyl sulfoxide;

DOI:10.1021/ol990048l

Reference yield:

C10H16O3 (238072-61-2) → C21H30O (238072-73-6)

Guidance literature:

Multi-step reaction with 8 steps

1.1: 98 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂ / -60 - 20 °C

2.1: NaH / tetrahydrofuran; various solvent(s) / 0.33 h / 20 °C

2.2: 91 percent / tetrahydrofuran; various solvent(s) / 1 h / 20 °C

3.1: 96 percent / K₂CO₃; MeOH / 2 h / 20 °C

4.1: 96 percent / imidazole; DMAP / CH₂Cl₂ / 2 h / 20 °C

5.1: DIBAL-H / diethyl ether; hexane / 5 h / -78 °C

6.1: BuLi / tetrahydrofuran; hexane / 0.17 h / 20 °C

6.2: 90 percent / tetrahydrofuran; hexane / 20 °C

7.1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 4 h / 70 °C

8.1: 80 percent / SO₃-pyridine; Et₃N / dimethylsulfoxide / 0.67 h / 20 °C

With 1H-imidazole; methanol; dmap; n-butyllithium; oxalyl dichloride; pyridine-SO₃ complex; tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; potassium carbonate; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; dimethyl sulfoxide; 1.1: Swern oxidation;

DOI:10.1021/ol990048l

upstream raw materials:

(1R,2S,7S)-6-[(E)-1-Methyl-3-(2,6,6-trimethyl-cyclohex-1-enyl)-prop-2-en-(E)-ylidene]-bicyclo[5.1.0]octan-2-ol

C₁₀H₁₆O₃

C₁₀H₁₄O₃

C₁₃H₁₇NO₂

Downstream raw materials:

C₂₃H₃₁N

C₂₃H₃₁N