Methyl 2-hydroxy-2-phenylhept-3-ynoate

Base Information

Chemical Name:Methyl 2-hydroxy-2-phenylhept-3-ynoate
CAS No.:92956-86-0
Molecular Formula:C₁₄H₁₆O₃
Molecular Weight:232.279
Hs Code.:
NSC Number:116013
DSSTox Substance ID:DTXSID90297442

Synonyms:92956-86-0;methyl 2-hydroxy-2-phenylhept-3-ynoate;NSC116013;DTXSID90297442;NSC-116013

Suppliers and Price of Methyl 2-hydroxy-2-phenylhept-3-ynoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyl 2-hydroxy-2-phenylhept-3-ynoate

Chemical Property:

Vapor Pressure:4.33E-06mmHg at 25°C
Boiling Point:368.8°Cat760mmHg
Flash Point:153.2°C
Density:1.125g/cm³
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:232.109944368
Heavy Atom Count:17
Complexity:317

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC#CC(C1=CC=CC=C1)(C(=O)OC)O

Technology Process of Methyl 2-hydroxy-2-phenylhept-3-ynoate

There total 1 articles about Methyl 2-hydroxy-2-phenylhept-3-ynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 15206-55-0
methyl 2-oxo-2-phenylacetate

: 627-19-0
1-Pentyne

: 92956-86-0
methyl 2-hydroxy-2-phenyl-hept-3-ynoate

Guidance literature:: 1-Pentyne; With ethylmagnesium bromide; In diethyl ether; for 2h; Reflux; Inert atmosphere;

methyl 2-oxo-2-phenylacetate; In diethyl ether; for 3.5h; Inert atmosphere; Reflux;
DOI:10.1002/hc.21096

Reference yield:

: 92956-86-0
methyl 2-hydroxy-2-phenyl-hept-3-ynoate

: C₁₄H₁₅Cl₂O₃P

Guidance literature:: With triethylamine; phosphorus trichloride; In diethyl ether; at -70 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/hc.21096

Reference yield:

: 92956-86-0
methyl 2-hydroxy-2-phenyl-hept-3-ynoate

: methyl 4-(benzenesulfinyl)-2-phenyl-hepta-2,3-dienoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / diethyl ether / 1 h / -70 °C / Inert atmosphere

2.1: diethyl ether / 7 h / 20 °C / Inert atmosphere

2.2: 7 h / 20 °C / Inert atmosphere

With triethylamine; In diethyl ether;
DOI:10.1002/hc.21096