Technology Process of Benzeneacetic acid, -alpha--methyl-4-(3-methyl-3-butenyl)- (9CI)
There total 3 articles about Benzeneacetic acid, -alpha--methyl-4-(3-methyl-3-butenyl)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
ethanol; water;
for 6h;
Ambient temperature;
DOI:10.1248/cpb.34.4653
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) bromoethane, magnesium, iodine; 2.) CuBr / 1.) diethyl ether, 25-30 deg C, 5 h; 2.) THF, reflux, 3 h
2: 1.) magnesium, 1,2-dibromoethane, iodine; 2.) NiCl2 / 1.) THF, 100-110 deg C, 2 h; 2.) THF, r.t., 4.5 h
3: 96 percent / NaOH / ethanol; H2O / 6 h / Ambient temperature
With
sodium hydroxide; ethyl bromide; iodine; magnesium; ethylene dibromide; copper(I) bromide; nickel dichloride;
In
ethanol; water;
DOI:10.1248/cpb.34.4653
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) magnesium, 1,2-dibromoethane, iodine; 2.) NiCl2 / 1.) THF, 100-110 deg C, 2 h; 2.) THF, r.t., 4.5 h
2: 96 percent / NaOH / ethanol; H2O / 6 h / Ambient temperature
With
sodium hydroxide; iodine; magnesium; ethylene dibromide; nickel dichloride;
In
ethanol; water;
DOI:10.1248/cpb.34.4653
