4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine

Base Information

Chemical Name:4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine
CAS No.:1198299-71-6
Molecular Formula:C₂₁H₂₁N₃O₆
Molecular Weight:411.414
Hs Code.:

Synonyms:4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine

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Technology Process of 4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine

There total 1 articles about 4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1198299-64-7
3-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]glutaric anhydride

: 1198299-71-6
4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine

Guidance literature:: With ammonia; In tetrahydrofuran; at 0 ℃; for 2h;

Reference yield: 62.0%

: 1198299-71-6
4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine

: 879126-98-4,879126-99-5,191732-72-6
Lenalidomide

Guidance literature:: 4-[4-(N-benzyloxycarbonyl)amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl]isoglutamine; With thionyl chloride; In N,N-dimethyl-formamide; at -20 ℃;

With ammonium formate; 5% Pd(II)/C(eggshell); In methanol; at 30 ℃; for 2h;