1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, (4R-trans)- (9CI)

Base Information

Chemical Name:1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, (4R-trans)- (9CI)
CAS No.:106622-89-3
Molecular Formula:C₈H₁₄O₃
Molecular Weight:158.197
Hs Code.:
Mol file:106622-89-3.mol

Synonyms:1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, (4R-trans)- (9CI)

Suppliers and Price of 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, (4R-trans)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, (4R-trans)- (9CI)

Chemical Property:

Boiling Point:65 - 70 °C (15 mmHg)
PSA：35.53000
LogP:1.11540

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, (4R-trans)- (9CI)

There total 8 articles about 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, (4R-trans)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 104417-89-2,104486-01-3,111319-75-6,124019-24-5
(2RS,3RS)-2,3-isopropylidenedioxy-2-methylbutan-1-ol

: 102103-81-1,106544-44-9,106622-88-2,106622-89-3
(2RS,3SR)-2,3-isopropylidenedioxy-2-methylbutanal

Guidance literature:: With Celite; pyridinium chlorochromate; In dichloromethane; for 24h; Ambient temperature;

Reference yield:

: 92010-40-7
3-hydroxy-3-methyl-5-phenylpent-4-en-2-one

: 102103-81-1,106544-44-9,106622-88-2,106622-89-3
(S)-2,2,4,5-Tetramethyl-[1,3]dioxolane-4-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / D-glucose / H₂O; ethanol / 12 h / 25 °C / bakers' yeast

2: 85 percent / 4-toluenesulfonic acid / benzene / 3 h / Heating

3: 1.) O₃, 2.) Ph₃P / 1.) CH₂Cl₂, -40 deg C, 2.) CH₂Cl₂, a) -40 deg C, 1 h, b) 23 deg C, 5 h

With D-glucose; toluene-4-sulfonic acid; ozone; triphenylphosphine; In ethanol; water; benzene;
DOI:10.1021/jo00382a032

Reference yield:

: 106544-28-9,106544-29-0
(2S,3RS)-2,3-dihydroxy-3-methyl-5-phenylpent-4-ene

: 102103-81-1,106544-44-9,106622-88-2,106622-89-3
(S)-2,2,4,5-Tetramethyl-[1,3]dioxolane-4-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / 4-toluenesulfonic acid / benzene / 3 h / Heating

2: 1.) O₃, 2.) Ph₃P / 1.) CH₂Cl₂, -40 deg C, 2.) CH₂Cl₂, a) -40 deg C, 1 h, b) 23 deg C, 5 h

With toluene-4-sulfonic acid; ozone; triphenylphosphine; In benzene;
DOI:10.1021/jo00382a032