3-bromo-4-nitro-5-pentylphenol methyl ether

Base Information

• Chemical Name: 3-bromo-4-nitro-5-pentylphenol methyl ether
• CAS No.: 110827-96-8
• Molecular Formula: C₁₂H₁₆BrNO₃
• Molecular Weight: 302.168
• Mol file: 110827-96-8.mol

Synonyms:3-bromo-4-nitro-5-pentylphenol methyl ether

Chemical Property of 3-bromo-4-nitro-5-pentylphenol methyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 3-bromo-4-nitro-5-pentylphenol methyl ether

There total 5 articles about 3-bromo-4-nitro-5-pentylphenol methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Benzyloxybenzaldehyde (1700-37-4) → 3-bromo-4-nitro-5-pentylphenol methyl ether (110827-96-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) Mg / 1.) ether, 2.) ether, a) RT, 1 h, b) reflux, 10 min

2: 92 percent / H₂, conc. aq. HCl / 10percent Pd/C / acetic acid

3: 71 percent / Br₂, Al / 0.25 h / Ambient temperature

4: 93 percent / AlCl₃ / benzene / 0.25 h / Heating

5: 30 percent / 70percent HNO₃, AcOH / 0.5 h / 10 - 12 °C

6: K₂CO₃ / dimethylformamide / Ambient temperature

With hydrogenchloride; aluminium trichloride; hydrogen; bromine; nitric acid; potassium carbonate; magnesium; acetic acid; aluminium; palladium on activated charcoal; In acetic acid; N,N-dimethyl-formamide; benzene;

Reference yield:

1-(3'-benzyloxyphenyl)pentan-1-ol (50673-94-4) → 3-bromo-4-nitro-5-pentylphenol methyl ether (110827-96-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 92 percent / H₂, conc. aq. HCl / 10percent Pd/C / acetic acid

2: 71 percent / Br₂, Al / 0.25 h / Ambient temperature

3: 93 percent / AlCl₃ / benzene / 0.25 h / Heating

4: 30 percent / 70percent HNO₃, AcOH / 0.5 h / 10 - 12 °C

5: K₂CO₃ / dimethylformamide / Ambient temperature

With hydrogenchloride; aluminium trichloride; hydrogen; bromine; nitric acid; potassium carbonate; acetic acid; aluminium; palladium on activated charcoal; In acetic acid; N,N-dimethyl-formamide; benzene;

Reference yield:

3-pentyl phenol (20056-66-0) → 3-bromo-4-nitro-5-pentylphenol methyl ether (110827-96-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 71 percent / Br₂, Al / 0.25 h / Ambient temperature

2: 93 percent / AlCl₃ / benzene / 0.25 h / Heating

3: 30 percent / 70percent HNO₃, AcOH / 0.5 h / 10 - 12 °C

4: K₂CO₃ / dimethylformamide / Ambient temperature

With aluminium trichloride; bromine; nitric acid; potassium carbonate; acetic acid; aluminium; In N,N-dimethyl-formamide; benzene;

upstream raw materials:

3-Benzyloxybenzaldehyde

3-pentyl phenol

1-(3'-benzyloxyphenyl)pentan-1-ol

3-bromo-5-pentylphenol

Downstream raw materials:

2-bromo-4-methoxy-6-pentylaniline