5-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one

Base Information

Chemical Name:5-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one
CAS No.:106429-58-7
Molecular Formula:C₈H₈N₂O₂
Molecular Weight:164.164
Hs Code.:
DSSTox Substance ID:DTXSID301224703
Mol file:106429-58-7.mol

Synonyms:106429-58-7;5-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one;5-(hydroxymethyl)-1,3-dihydrobenzimidazol-2-one;2H-Benzimidazol-2-one,1,3-dihydro-5-(hydroxymethyl)-(9CI);5-(Hydroxymethyl)benzimidazol-2(3H)-one;SCHEMBL5312605;SCHEMBL9619832;UBXKTZMRHQPCFZ-UHFFFAOYSA-N;DTXSID301224703;MFCD18814456;AKOS009332634;SY343142;2,3-Dihydro-2-oxo-5-hydroxymethyl-1H-benzimidazole;1,3-Dihydro-5-(hydroxymethyl)-2H-benzimidazol-2-one;2h-benzimidazol-2-one,1,3-dihydro-5-(hydroxymethyl)-

Suppliers and Price of 5-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
2-Hydroxy-5-hydroxymethyl-1H-benzimidazole
10g
$ 3139.22

Total 1 raw suppliers

Chemical Property of 5-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one

Chemical Property:

PSA：68.88000
LogP:0.34850
XLogP3:-0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:164.058577502
Heavy Atom Count:12
Complexity:196

Purity/Quality:: 2-Hydroxy-5-hydroxymethyl-1H-benzimidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1CO)NC(=O)N2

Technology Process of 5-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one

There total 2 articles about 5-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 2-oxo-2,3-dihydro-1H-benzoimidazole-5-carboxylic acid ethyl ester

: 106429-58-7
5-hydroxymethyl-1,3-dihydro-benzoimidazol-2-one

Guidance literature:: 2-oxo-2,3-dihydro-1H-benzoimidazole-5-carboxylic acid ethyl ester; With diisobutylaluminium hydride; In tetrahydrofuran; toluene; at 0 ℃;

With water; Rochelle's salt; In tetrahydrofuran; toluene;

Reference yield:

: 106429-57-6
1,3-dihydro-2-oxo-2H-benzimidazole-5-carboxylic acid methyl ester

: 106429-58-7
5-hydroxymethyl-1,3-dihydro-benzoimidazol-2-one

Guidance literature:: With diisobutylaluminium hydride; In tetrahydrofuran; toluene;

Reference yield: 70.0%

: 106429-58-7
5-hydroxymethyl-1,3-dihydro-benzoimidazol-2-one

: 106429-59-8
2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbaldehyde

Guidance literature:: 2,3-Dihydro-2-oxo-5-hydroxymethyl-1H-benzimidazole; With Dess-Martin periodane; In tetrahydrofuran; at 20 ℃;

With sodium hydrogencarbonate; In tetrahydrofuran; water; ethyl acetate;