Technology Process of Formic acid (1S,2S)-2-(3-ethoxycarbonyloxy-3-methyl-pent-4-enyl)-1,3,3-trimethyl-cyclohexyl ester
There total 14 articles about Formic acid (1S,2S)-2-(3-ethoxycarbonyloxy-3-methyl-pent-4-enyl)-1,3,3-trimethyl-cyclohexyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 8 steps
1.1: 99 percent / Pb(OAc)4; I2 / benzene / 4 h / 50 - 60 °C / Irradiation
2.1: 82 percent / t-BuOK / various solvent(s); dimethylsulfoxide / 4 h / 20 °C
3.1: 88 percent / KOH / methanol / 2 h / 20 °C
4.1: O3 / CH2Cl2 / 0.75 h / -78 °C
4.2: 88 percent / NaBH4 / methanol / 0.5 h / 20 °C
5.1: 90 percent / aq. NaIO4 / 2-methyl-propan-2-ol / 4 h / 20 °C
6.1: 95 percent / MCPBA; NaHCO3 / CH2Cl2 / 3 h / Heating
7.1: tetrahydrofuran / 0.75 h / 0 °C
8.1: tetrahydrofuran / 13 h / 20 °C
With
lead(IV) acetate; potassium hydroxide; sodium periodate; potassium tert-butylate; iodine; sodium hydrogencarbonate; ozone; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; tert-butyl alcohol; benzene;
1.1: Decarboxylation / 2.1: Dehydroiodination / 3.1: Substitution / 4.1: Oxidation / 4.2: Reduction / 5.1: Ring cleavage / 6.1: Oxidation / 7.1: Grignard reaction / 8.1: Acylation;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 95 percent / MCPBA; NaHCO3 / CH2Cl2 / 3 h / Heating
2: tetrahydrofuran / 0.75 h / 0 °C
3: tetrahydrofuran / 13 h / 20 °C
With
sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane;
1: Oxidation / 2: Grignard reaction / 3: Acylation;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: O3 / CH2Cl2 / 0.75 h / -78 °C
1.2: 88 percent / NaBH4 / methanol / 0.5 h / 20 °C
2.1: 90 percent / aq. NaIO4 / 2-methyl-propan-2-ol / 4 h / 20 °C
3.1: 95 percent / MCPBA; NaHCO3 / CH2Cl2 / 3 h / Heating
4.1: tetrahydrofuran / 0.75 h / 0 °C
5.1: tetrahydrofuran / 13 h / 20 °C
With
sodium periodate; sodium hydrogencarbonate; ozone; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; tert-butyl alcohol;
1.1: Oxidation / 1.2: Reduction / 2.1: Ring cleavage / 3.1: Oxidation / 4.1: Grignard reaction / 5.1: Acylation;
