[2-(2-Morpholinoethoxy)phenyl]methanol

Base Information

• Chemical Name: [2-(2-Morpholinoethoxy)phenyl]methanol
• CAS No.: 106276-04-4
• Molecular Formula: C13H19 N O3
• Molecular Weight: 237.29
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID20428202
• Mol file: 106276-04-4.mol

Synonyms:[2-(2-morpholinoethoxy)phenyl]methanol;106276-04-4;[2-(2-morpholin-4-ylethoxy)phenyl]methanol;{2-[2-(morpholin-4-yl)ethoxy]phenyl}methanol;(2-(2-Morpholinoethoxy)phenyl)methanol;SCHEMBL7123326;DTXSID20428202;MJDMCSJTOOAYPS-UHFFFAOYSA-N;MFCD07772843;AKOS000247996;MS-22280;CS-0339537;[2-(2-morpholin-4-yl-ethoxy)-phenyl]-methanol;W-204605

Chemical Property of [2-(2-Morpholinoethoxy)phenyl]methanol

Chemical Property:

• Vapor Pressure: 7.12E-07mmHg at 25°C
• Melting Point: 80 °C
• Refractive Index: 1.542
• Boiling Point: 392.8°Cat760mmHg
• Flash Point: 191.3°C
• PSA: 41.93000
• Density: 1.138g/cm³
• LogP: 0.82780
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 237.13649347
• Heavy Atom Count: 17
• Complexity: 207

Purity/Quality:

97% ^*data from raw suppliers

[2-(2-MORPHOLINO ETHOXY)PHENYL]METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1CCOC2=CC=CC=C2CO

Technology Process of [2-(2-Morpholinoethoxy)phenyl]methanol

There total 2 articles about [2-(2-Morpholinoethoxy)phenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

salicylic alcohol (90-01-7) + 4-(2-chloroethyl)morpholine hydrochride (3647-69-6) → 2-(2-morpholino-ethoxy)-benzyl alcohol (106276-04-4)

Guidance literature:

In sodium hydroxide; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Reference yield:

N-(2-chlorethyl)morpholine (3240-94-6) + salicylic alcohol (90-01-7) → 2-(2-morpholino-ethoxy)-benzyl alcohol (106276-04-4)

Guidance literature:

With methanol; sodium methylate;

Reference yield: 92.0%

2-(2-morpholino-ethoxy)-benzyl alcohol (106276-04-4) → 2-(2-morpholinoethoxy)benzonitrile

Guidance literature:

With ammonium hydroxide; In tert-butyl alcohol; at 130 ℃; for 24h; under 7500.75 Torr; Sealed tube; Autoclave;

DOI:10.1016/j.chempr.2021.12.001

upstream raw materials:

N-(2-chlorethyl)morpholine

salicylic alcohol

4-(2-chloroethyl)morpholine hydrochride

Downstream raw materials:

4-[2-(2-chloromethyl-phenoxy)-ethyl]-morpholine; hydrochloride