diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate

Base Information

• Chemical Name: diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate
• CAS No.: 174655-64-2
• Molecular Formula: C₂₈H₃₁NO₄Se
• Molecular Weight: 524.518
• Mol file: 174655-64-2.mol

Synonyms:diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate

Chemical Property of diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate

There total 3 articles about diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (3S)-2-oxotetrahydrofuran-3-ylcarbamate (40856-59-5,132957-40-5) → diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate (174655-64-2)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / dimethylformamide / 1 h / 100 °C

2: ethyl acetate

With sodium tetrahydroborate; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1055/s-1996-4177

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate (174655-64-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / Et₃N / CH₂Cl₂ / 12 h / Ambient temperature

2: NaBH₄ / dimethylformamide / 1 h / 100 °C

3: ethyl acetate

With sodium tetrahydroborate; triethylamine; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1055/s-1996-4177

Reference yield:

(S)-2-((tert-butoxycarbonyl)amino)-4-(phenylselanyl)butanoic acid (1028258-40-3) + diazodiphenylmethane (908093-98-1) → diphenylmethyl N-(tert-butoxycarbonyl)-2-<2'-(phenylseleno)ethyl>glycinate (174655-64-2)

Guidance literature:

In ethyl acetate; Yield given;

DOI:10.1055/s-1996-4177

upstream raw materials:

(S)-2-((tert-butoxycarbonyl)amino)-4-(phenylselanyl)butanoic acid

diazodiphenylmethane

di-tert-butyl dicarbonate

tert-butyl (3S)-2-oxotetrahydrofuran-3-ylcarbamate

Downstream raw materials:

diphenylmethyl N-(tert-butoxycarbonyl)-2-vinylglycinate