(E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

Base Information

Chemical Name:(E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole
CAS No.:1174549-28-0
Molecular Formula:C₃₂H₄₀N₄O₃SSi
Molecular Weight:588.846
Hs Code.:

Synonyms:(E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

Suppliers and Price of (E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

There total 11 articles about (E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1174549-39-3
(S,E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)thio)-1-phenyl-1H-tetrazole

: 1174549-28-0
(E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

Guidance literature:: With hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide; In ethanol; water; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/chem.201501304

Reference yield:

: 5390-04-5
pent-1-yn-5-ol

: 1174549-28-0
(E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

Guidance literature:: Multi-step reaction with 10 steps

1.1: 1H-imidazole / dichloromethane / 0.5 h / 0 - 20 °C / Inert atmosphere

2.1: n-butyllithium / hexane; tetrahydrofuran / 2 h / -78 °C / Inert atmosphere

2.2: 1.5 h / -78 - 20 °C / Inert atmosphere

3.1: sodium bis(2-methoxyethoxy)aluminium dihydride / diethyl ether; toluene / 4 h / 0 - 20 °C / Inert atmosphere

4.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 1 h / 20 °C / Inert atmosphere

5.1: lithium diisopropyl amide / hexane; tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

5.2: 3.5 h / -78 - -20 °C / Inert atmosphere

6.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C / Inert atmosphere

7.1: 1H-imidazole; dmap / dichloromethane / 1 h / 0 °C

8.1: water; hydrogenchloride / tetrahydrofuran / 1 h / 20 °C

9.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 1.5 h / 0 °C

10.1: hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide / ethanol; water / 12 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; hydrogenchloride; dmap; lithium aluminium tetrahydride; n-butyllithium; hexaammonium heptamolybdate tetrahydrate; water; dihydrogen peroxide; iodine; triphenylphosphine; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide; diethylazodicarboxylate; In tetrahydrofuran; diethyl ether; ethanol; hexane; dichloromethane; water; toluene; 5.1: |Evans Aldol Reaction / 5.2: |Evans Aldol Reaction / 9.1: |Mitsunobu Displacement;
DOI:10.1002/chem.201501304

Reference yield:

: 61362-77-4
5-[tert-butyldimethylsilyloxy]pent-1-yne

: 1174549-28-0
(E)-5-((8-(tert-butyldiphenylsiloxy)-7-methyloct-4-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

Guidance literature:: Multi-step reaction with 9 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / 2 h / -78 °C / Inert atmosphere

1.2: 1.5 h / -78 - 20 °C / Inert atmosphere

2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / diethyl ether; toluene / 4 h / 0 - 20 °C / Inert atmosphere

3.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 1 h / 20 °C / Inert atmosphere

4.1: lithium diisopropyl amide / hexane; tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

4.2: 3.5 h / -78 - -20 °C / Inert atmosphere

5.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C / Inert atmosphere

6.1: 1H-imidazole; dmap / dichloromethane / 1 h / 0 °C

7.1: water; hydrogenchloride / tetrahydrofuran / 1 h / 20 °C

8.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 1.5 h / 0 °C

9.1: hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide / ethanol; water / 12 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; hydrogenchloride; dmap; lithium aluminium tetrahydride; n-butyllithium; hexaammonium heptamolybdate tetrahydrate; water; dihydrogen peroxide; iodine; triphenylphosphine; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide; diethylazodicarboxylate; In tetrahydrofuran; diethyl ether; ethanol; hexane; dichloromethane; water; toluene; 4.1: |Evans Aldol Reaction / 4.2: |Evans Aldol Reaction / 8.1: |Mitsunobu Displacement;
DOI:10.1002/chem.201501304