5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline

Base Information

• Chemical Name: 5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline
• CAS No.: 1093409-41-6
• Molecular Formula: C₂₆H₂₇NO₅
• Molecular Weight: 433.504
• Mol file: 1093409-41-6.mol

Synonyms:5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline

Chemical Property of 5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline

There total 1 articles about 5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5,12-dimethyl-2-trifluoroacetyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline (1093409-40-5) → 5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline (1093409-41-6)

Guidance literature:

With sodium hydroxide; water; In methanol; at 20 ℃; for 12h;

DOI:10.1016/j.tet.2008.09.097

Reference yield: 69.0%

5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline (1093409-41-6) → 5,12-dimethyl-1-(3',4',5-trimethoxyphenyl)benzodioxino[2,3-g]isoquinoline (1093409-43-8)

Guidance literature:

With 10% Pd/C; In decalin; at 220 ℃; for 24h;

DOI:10.1016/j.tet.2008.09.097

Reference yield: 67.0%

methyl 6-bromohexanoate (14273-90-6) + 5,12-dimethyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline (1093409-41-6) → C33H39NO7 (1093409-46-1)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 60h;

DOI:10.1016/j.tet.2008.09.097

upstream raw materials:

5,12-dimethyl-2-trifluoroacetyl-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydrobenzodioxino[2,3-g]isoquinoline

Downstream raw materials:

5,12-dimethyl-1-(3',4',5-trimethoxyphenyl)benzodioxino[2,3-g]isoquinoline

C₂₆H₂₅NO₅

C₃₃H₃₉NO₇

C₃₂H₄₀N₂O₅