3-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-1-phenylpropan-2-yl isonicotinate

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Chemical Name:3-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-1-phenylpropan-2-yl isonicotinate
CAS No.:1196085-30-9
Molecular Formula:C₂₁H₁₆N₄O₃
Molecular Weight:372.383
Hs Code.:

Synonyms:3-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-1-phenylpropan-2-yl isonicotinate

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Chemical Property of 3-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-1-phenylpropan-2-yl isonicotinate

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Technology Process of 3-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-1-phenylpropan-2-yl isonicotinate

There total 2 articles about 3-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-1-phenylpropan-2-yl isonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.2%

: 55-22-1
pyridine-4-carboxylic acid

: 1196085-36-5
C₁₅H₁₂BrN₃O

: 1196085-30-9
3-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-1-phenylpropan-2-yl isonicotinate

Guidance literature:: With triethylamine; In acetone; at 0 ℃; for 5h; Cooling with ice;
DOI:10.1007/s00044-009-9243-3

Reference yield:

: 28918-19-6
3-(1H-benzo[d]-1,2,3-triazol-1-yl)-1-phenylpropan-1-one

: 1196085-30-9
3-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-1-phenylpropan-2-yl isonicotinate

Guidance literature:: Multi-step reaction with 2 steps

1: bromine; sodium acetate / acetic acid / 20 °C

2: triethylamine / acetone / 5 h / 0 °C / Cooling with ice

With bromine; sodium acetate; triethylamine; In acetic acid; acetone;
DOI:10.1007/s00044-009-9243-3