Technology Process of C32H27F3N10O2
There total 11 articles about C32H27F3N10O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
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Multi-step reaction with 3 steps
1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C
3: tris(2-carboxyethyl)phosphine / 2 h / 20 °C
With
tris(2-carboxyethyl)phosphine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja306035v
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine triflouroacetate / dimethyl sulfoxide / 95 °C
2: potassium carbonate / N,N-dimethyl-formamide / 20 °C
3: trifluoroacetic acid / dichloromethane / 1 h / 20 °C
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C
5: tris(2-carboxyethyl)phosphine / 2 h / 20 °C
With
tris(2-carboxyethyl)phosphine; triethylamine triflouroacetate; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/ja306035v
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C
2: tris(2-carboxyethyl)phosphine / 2 h / 20 °C
With
tris(2-carboxyethyl)phosphine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
DOI:10.1021/ja306035v